- Vacant & Abandoned Shotgun Houses, which are in dwindling supply in the city
- Colonial Gardens, described as a "dilapidated reminder of the South End's colorful past, historic value and uncertain future."
- Mid-century modern structures are not old enough to be recognized by enough people for their signficance and too few steps are being taken to preserve the era's architecture
- Ouerbacker House, 1633 W. Jefferson Street, ca. 1860-1865.
- Corner store fronts of retail establishments from antebellum to midcentury were staples of American life as we shopped in the local general store.
- Roscoe Goose house, 3012 S. Third St., ca. 1900, was occupied by the jockey who rode 91-1 Donerail to victory in the 1913 Kentucky Derby.
- Lampton Baptist Church, located at 850 S. Fourth Street, was founded in 1866.
- Doerhorfer house, 422 W. Broadway, was designated a city landmark in 2011. Despite the designation, the 2 1/2 story frame structure remains at risk.
- Historic Old Clarksville Site in Indiana is where George Rogers Clark built his cabin and mill. It is a key part of Kentuckiana history and must be protected for future generations.
- Water Co. Block downtown Louisville contains many older structures utilized by the old water company. A mixed use development proposal puts them at risk.
Louisville's Most Endangered Properties
Preservation Louisville has released the names of the community's most endangered historic properties.